BDBM50078558 5-[(3R,3aS,8aS)-2-Oxo-1-(5-phenyl-pentyl)-1,2,3,3a,8,8a-hexahydro-indeno[2,1-b]pyrrol-3-yl]-pentanamidine::CHEMBL46923

SMILES NC(=N)CCCC[C@@H]1[C@@H]2[C@H](Cc3ccccc23)N(CCCCCc2ccccc2)C1=O

InChI Key InChIKey=QKUOYYOPSMNOBQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078558   

TargetSerine protease 1(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078558(5-[(3R,3aS,8aS)-2-Oxo-1-(5-phenyl-pentyl)-1,2,3,3a...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078558(5-[(3R,3aS,8aS)-2-Oxo-1-(5-phenyl-pentyl)-1,2,3,3a...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078558(5-[(3R,3aS,8aS)-2-Oxo-1-(5-phenyl-pentyl)-1,2,3,3a...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed