BDBM50078588 1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-pyridin-2-ylsulfanyl]-2-methyl-propan-2-ol::CHEMBL300710

SMILES CC(C)(O)CSc1ncc(cc1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=DHNTZEYGEFMOTJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078588   

TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078588(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078588(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078588(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in CHO whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed