BDBM50078593 CHEMBL49394::[3'-(4-Methanesulfonyl-phenyl)-5'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3-yl]-methanol

SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(cnc1N1CCCC(CO)C1)C(F)(F)F

InChI Key InChIKey=KVUASUDFPOEMLR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078593   

TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078593([3'-(4-Methanesulfonyl-phenyl)-5'-trifluoromethyl-...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078593([3'-(4-Methanesulfonyl-phenyl)-5'-trifluoromethyl-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078593([3'-(4-Methanesulfonyl-phenyl)-5'-trifluoromethyl-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in CHO whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed