BDBM50078650 CHEMBL51645::N-[5-(3-Dimethylaminomethyl-5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepine-10-carbonyl)-pyridin-2-yl]-5-fluoro-2-methyl-benzamide

SMILES CN(C)Cc1ccc2CN(C(=O)c3ccc(NC(=O)c4cc(F)ccc4C)nc3)c3ccccc3Cn12

InChI Key InChIKey=ZYEZQNYEPMBWQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078650   

TargetVasopressin V1a receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50078650(N-[5-(3-Dimethylaminomethyl-5H,11H-benzo[e]pyrrolo...)
Affinity DataIC50: 99nMAssay Description:In vitro inhibition of (Phe-3,4,5 [3H]-) AVP binding towards isolated rat hepatic Vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50078650(N-[5-(3-Dimethylaminomethyl-5H,11H-benzo[e]pyrrolo...)
Affinity DataIC50: 33nMAssay Description:In vitro inhibition of (P[3H]-AVP binding towards isolated rat kidney medullary Vasopre ssin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed