BDBM50078683 3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one::CHEMBL51434

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccc(F)cc1

InChI Key InChIKey=ZRCURVJXQGLLOZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50078683   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078683(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against human whole cells (CHO) Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078683(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078683(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 4.70E+3nMAssay Description:In vitro inhibitory activity against human whole cells Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078683(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro for its inhibitory activity against human whole blood Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed