BDBM50078786 1-(4-octylpyrimidin-2-yl)-N-phenyl-2,3-dihydro-1H-indole-5-sulfonamide::CHEMBL53359

SMILES CCCCCCCCc1ccnc(n1)N1CCc2cc(ccc12)S(=O)(=O)Nc1ccccc1

InChI Key InChIKey=WQMUWTUKVXWONB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078786   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078786(1-(4-octylpyrimidin-2-yl)-N-phenyl-2,3-dihydro-1H-...)
Affinity DataIC50: 530nMAssay Description:In vitro binding affinity towards cloned human beta-2 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078786(1-(4-octylpyrimidin-2-yl)-N-phenyl-2,3-dihydro-1H-...)
Affinity DataEC50:  2.40nMAssay Description:In vitro agonistic activity against cloned human beta-3 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078786(1-(4-octylpyrimidin-2-yl)-N-phenyl-2,3-dihydro-1H-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards cloned human beta-1 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed