BDBM50078792 4-[methyl(4-octyl-1,3-thiazol-2-yl)amino]-N-phenylbenzene-1-sulfonamide::CHEMBL56767

SMILES CCCCCCCCc1csc(n1)N(C)c1ccc(cc1)S(=O)(=O)Nc1ccccc1

InChI Key InChIKey=NICNBEWVHFQQFR-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078792   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078792(4-[methyl(4-octyl-1,3-thiazol-2-yl)amino]-N-phenyl...)
Affinity DataIC50: 440nMAssay Description:In vitro binding affinity towards cloned human beta-2 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078792(4-[methyl(4-octyl-1,3-thiazol-2-yl)amino]-N-phenyl...)
Affinity DataEC50:  5.5nMAssay Description:In vitro agonistic activity against cloned human beta-3 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078792(4-[methyl(4-octyl-1,3-thiazol-2-yl)amino]-N-phenyl...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro binding affinity towards cloned human beta-1 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed