BDBM50078796 1-[6-(3-cyclopentylpropyl)pyridin-2-yl]-N-phenyl-2,3-dihydro-1H-indole-5-sulfonamide::CHEMBL433252

SMILES O=S(=O)(Nc1ccccc1)c1ccc2N(CCc2c1)c1cccc(CCCC2CCCC2)n1

InChI Key InChIKey=KJBYOLPMFLIWTF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078796   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078796(1-[6-(3-cyclopentylpropyl)pyridin-2-yl]-N-phenyl-2...)
Affinity DataIC50: 450nMAssay Description:In vitro binding affinity towards cloned human beta-2 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078796(1-[6-(3-cyclopentylpropyl)pyridin-2-yl]-N-phenyl-2...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro binding affinity towards cloned human beta-1 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078796(1-[6-(3-cyclopentylpropyl)pyridin-2-yl]-N-phenyl-2...)
Affinity DataEC50:  1.70nMAssay Description:In vitro agonistic activity against cloned human beta-3 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed