BDBM50078809 1-[4-(3-cyclopentylpropyl)-1,3-thiazol-2-yl]-N-phenyl-2,3-dihydro-1H-indole-5-sulfonamide::CHEMBL55541

SMILES O=S(=O)(Nc1ccccc1)c1ccc2N(CCc2c1)c1nc(CCCC2CCCC2)cs1

InChI Key InChIKey=UBEDCHWEFAXZEN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078809   

TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078809(1-[4-(3-cyclopentylpropyl)-1,3-thiazol-2-yl]-N-phe...)
Affinity DataEC50:  3.20nMAssay Description:In vitro agonistic activity against cloned human beta-3 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078809(1-[4-(3-cyclopentylpropyl)-1,3-thiazol-2-yl]-N-phe...)
Affinity DataIC50: 900nMAssay Description:In vitro binding affinity towards cloned human beta-2 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078809(1-[4-(3-cyclopentylpropyl)-1,3-thiazol-2-yl]-N-phe...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro binding affinity towards cloned human beta-1 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed