BDBM50078825 CHEMBL83148::N-Phenyl-benzenesulfonamide::phenyl(phenylsulfonyl)amine

SMILES O=S(=O)(Nc1ccccc1)c1ccccc1

InChI Key InChIKey=XAUGWFWQVYXATQ-UHFFFAOYSA-N

Data  2 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50078825   

TargetSerine/threonine-protein kinase mTOR(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50078825(phenyl(phenylsulfonyl)amine | N-Phenyl-benzenesulf...)
Affinity DataKd:  1.00E+6nMAssay Description:Dissociation constant when binding to FK506 binding protein (FKBP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50078825(phenyl(phenylsulfonyl)amine | N-Phenyl-benzenesulf...)
Affinity DataKd:  1.10E+6nMAssay Description:Binding affinity to human recombinant His-tagged Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissoc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50078825(phenyl(phenylsulfonyl)amine | N-Phenyl-benzenesulf...)
Affinity DataKd:  6.00E+5nMAssay Description:Binding affinity to human recombinant His-tagged Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) by saturation tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50078825(phenyl(phenylsulfonyl)amine | N-Phenyl-benzenesulf...)
Affinity DataIC50: 9.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50078825(phenyl(phenylsulfonyl)amine | N-Phenyl-benzenesulf...)
Affinity DataIC50: 2.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed