BDBM50079233 3-(3-Carbamimidoyl-phenyl)-5-ethanesulfonylmethyl-4,5-dihydro-isoxazole-5-carboxylic acid [5-(2-sulfamoyl-phenyl)-pyrimidin-2-yl]-amide; TFA::CHEMBL328805

SMILES CCS(=O)(=O)CC1(CC(=NO1)c1cccc(c1)C(N)=N)C(=O)Nc1ncc(cn1)-c1ccccc1S(N)(=O)=O

InChI Key InChIKey=WVAOHMVBVSDJQO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079233   

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079233(3-(3-Carbamimidoyl-phenyl)-5-ethanesulfonylmethyl-...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079233(3-(3-Carbamimidoyl-phenyl)-5-ethanesulfonylmethyl-...)
Affinity DataKi:  290nMAssay Description:Binding affinity towards trypsin obtained from human purified enzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079233(3-(3-Carbamimidoyl-phenyl)-5-ethanesulfonylmethyl-...)
Affinity DataKi:  1.30E+4nMAssay Description:Binding affinity towards thrombin obtained from human purified enzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed