BDBM50079246 3-(3-Carbamimidoyl-phenyl)-5-[1,2,4]triazol-1-ylmethyl-4,5-dihydro-isoxazole-5-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide; TFA::CHEMBL436684

SMILES NC(=N)c1cccc(c1)C1=NOC(Cn2cncn2)(C1)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O

InChI Key InChIKey=JIAYVDPPILTWKJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079246   

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079246(3-(3-Carbamimidoyl-phenyl)-5-[1,2,4]triazol-1-ylme...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079246(3-(3-Carbamimidoyl-phenyl)-5-[1,2,4]triazol-1-ylme...)
Affinity DataKi:  47nMAssay Description:Binding affinity towards trypsin obtained from human purified enzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079246(3-(3-Carbamimidoyl-phenyl)-5-[1,2,4]triazol-1-ylme...)
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity towards thrombin obtained from human purified enzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed