BDBM50079251 3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4,5-dihydro-isoxazole-5-carboxylic acid (2'-methylsulfamoyl-biphenyl-4-yl)-amide; TFA::CHEMBL321530

SMILES CNS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2(Cn3cnnn3)CC(=NO2)c2cccc(c2)C(N)=N)cc1

InChI Key InChIKey=CPMPNWOJBUGGMU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079251   

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079251(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  0.920nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079251(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  49nMAssay Description:Binding affinity towards trypsin obtained from human purified enzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079251(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards thrombin obtained from human purified enzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed