BDBM50079399 CHEMBL3417186

SMILES ONC(=O)CCCCCN1C\C=C\CCOc2cccc(c2)-c2ccnc(Nc3cccc(C1)c3)n2

InChI Key InChIKey=HORXOQNHKZICIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079399   

TargetTyrosine-protein kinase JAK2(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50079399(CHEMBL3417186)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human recombinant JAK2 using Z'LYTETry6 peptide substrate after 1 hr by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50079399(CHEMBL3417186)
Affinity DataIC50: 108nMAssay Description:Inhibition of human recombinant FLT3 after 1 hr by LanthaScreen assay platformMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50079399(CHEMBL3417186)
Affinity DataIC50: 152nMAssay Description:Inhibition of HDAC (unknown origin) using Fluor de Lys substrate after 2 hrs by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed