BDBM50079400 CHEMBL3417185

SMILES ONC(=O)CCCCN1C\C=C\CCOc2cccc(c2)-c2ccnc(Nc3cccc(C1)c3)n2

InChI Key InChIKey=VKJSVLBZCFXNIE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079400   

TargetTyrosine-protein kinase JAK2(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50079400(CHEMBL3417185)
Affinity DataIC50: 293nMAssay Description:Inhibition of human recombinant JAK2 using Z'LYTETry6 peptide substrate after 1 hr by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50079400(CHEMBL3417185)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant FLT3 after 1 hr by LanthaScreen assay platformMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50079400(CHEMBL3417185)
Affinity DataIC50: 251nMAssay Description:Inhibition of HDAC (unknown origin) using Fluor de Lys substrate after 2 hrs by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed