BDBM50079471 CHEMBL3417198

SMILES Cc1c(sc2ncnc(Nc3cc(C)cn(C)c3=O)c12)C(O)=O

InChI Key InChIKey=HSJFJXIKCSINLE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50079471   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Ocean University of China and Laboratory For Marine Drugs and Bioproducts

Curated by ChEMBL
LigandPNGBDBM50079471(CHEMBL3417198)
Affinity DataKi:  300nMAssay Description:Binding affinity to MNK1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Ocean University of China and Laboratory For Marine Drugs and Bioproducts

Curated by ChEMBL
LigandPNGBDBM50079471(CHEMBL3417198)
Affinity DataKi:  300nMAssay Description:Binding affinity to MNK2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Ocean University of China and Laboratory For Marine Drugs and Bioproducts

Curated by ChEMBL
LigandPNGBDBM50079471(CHEMBL3417198)
Affinity DataKi:  350nMAssay Description:Inhibition of Mnk2 (unknown origin) pre-incubated for 10 mins before eIF4E peptide substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Ocean University of China and Laboratory For Marine Drugs and Bioproducts

Curated by ChEMBL
LigandPNGBDBM50079471(CHEMBL3417198)
Affinity DataKi:  4.82E+3nMAssay Description:Inhibition of Mnk1 (unknown origin) pre-incubated for 10 mins before eIF4E peptide substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed