BDBM50079697 3-(3-tert-Butyl-benzofuran-2-ylsulfanyl)-4-hydroxy-6-phenethyl-6-phenyl-5,6-dihydro-pyran-2-one::CHEMBL293860

SMILES CC(C)(C)c1c(SC2C(=O)CC(CCc3ccccc3)(OC2=O)c2ccccc2)oc2ccccc12

InChI Key InChIKey=NYIJDWCYXLYCCN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079697   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079697(3-(3-tert-Butyl-benzofuran-2-ylsulfanyl)-4-hydroxy...)
Affinity DataIC50: 11nMpH: 4.7Assay Description:Inhibitory activity was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50079697(3-(3-tert-Butyl-benzofuran-2-ylsulfanyl)-4-hydroxy...)
Affinity DataIC50: 210nMpH: 6.2Assay Description:Inhibitory activity was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 6.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed