BDBM500800 7-[[5-(4- hydroxy-1- piperidyl)-2- pyridyl]amino] 4-pyrazolo[1,5- a]pyridin-3-yl- 2,3-dihydropyrrolo [3,4-c]pyridin- l-one::US11021481, Compound I-464::US11078201, Compound I-464::US11548890, Compound I-464

SMILES OC1CCN(CC1)c1ccc(Nc2cnc(c3CNC(=O)c23)-c2cnn3ccccc23)nc1

InChI Key InChIKey=KDDYNDQYGUOMGL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500800   

LigandPNGBDBM500800(7-[[5-(4- hydroxy-1- piperidyl)-2- pyridyl]amino] ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500800(7-[[5-(4- hydroxy-1- piperidyl)-2- pyridyl]amino] ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM500800(7-[[5-(4- hydroxy-1- piperidyl)-2- pyridyl]amino] ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500800(7-[[5-(4- hydroxy-1- piperidyl)-2- pyridyl]amino] ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500800(7-[[5-(4- hydroxy-1- piperidyl)-2- pyridyl]amino] ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent