BDBM50080290 (1R,2R)-2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-indan-1-ol::CHEMBL441806

SMILES Cc1[nH]c2nc(nc(N[C@@H]3Cc4ccccc4[C@H]3O)c2c1C)-c1ccccc1

InChI Key InChIKey=AQAMSAQCNMJLLH-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50080290   

TargetAdenosine receptor A1(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080290((1R,2R)-2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]...)
Affinity DataKi:  896nMAssay Description:Inhibitory activity against binding of the [3H]DPCPX to human A1 receptor (hA1) radioligands using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080290((1R,2R)-2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against membranes from yeast cells transformed with human A1 receptor (hA1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080290((1R,2R)-2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibitory activity against binding of [3H]DPCPX to human A1 receptor (hA1) using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080290((1R,2R)-2-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 3.22E+3nMAssay Description:Inhibitory activity against membranes from HEK293 cells stably expressing the human A2a receptor (hA2a)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed