BDBM50080292 4-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-cyclohexanol::CHEMBL78595

SMILES Cc1[nH]c2nc(nc(N[C@H]3CC[C@H](O)CC3)c2c1C)-c1ccccc1

InChI Key InChIKey=HLFGYAZPYDYTFN-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50080292   

TargetAdenosine receptor A1(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080292(4-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataKi:  25nMAssay Description:Inhibitory activity against binding of the [3H]DPCPX to human A1 receptor (hA1) radioligands using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080292(4-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against binding of the [3H]DPCPX to human A1 receptor (hA1) radioligands using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080292(4-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50: 49nMAssay Description:Inhibitory activity against binding of [3H]DPCPX to human A1 receptor (hA1) using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080292(4-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataKi:  754nMAssay Description:Inhibitory activity against binding of the [3H]CGS-21680 to human A2a receptor (hA2a) radioligands using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080292(4-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibitory activity against binding of [3H]CGS-21680 to human A2a receptor (hA2a) using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Cadus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080292(4-(5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibitory activity against membranes from HEK293 cells stably expressing the human A2a receptor (hA2a)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed