BDBM500803 4-(8-fluoro-7- methyl-imidazo[1,2- a]pyridin-3- yl)-7-[[5- (morpholino- methyl)-2- pyridyl]amino] isoindolin-1-one::US11021481, Compound I-468::US11548890, Compound I-468

SMILES Cc1ccn2c(cnc2c1F)-c1ccc(Nc2ccc(CN3CCOCC3)cn2)c2C(=O)NCc12

InChI Key InChIKey=YTTSULQSGVFROO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 500803   

LigandPNGBDBM500803(4-(8-fluoro-7- methyl-imidazo[1,2- a]pyridin-3- yl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500803(4-(8-fluoro-7- methyl-imidazo[1,2- a]pyridin-3- yl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

LigandPNGBDBM500803(4-(8-fluoro-7- methyl-imidazo[1,2- a]pyridin-3- yl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500803(4-(8-fluoro-7- methyl-imidazo[1,2- a]pyridin-3- yl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent