BDBM50080474 3-[(S)-3-(4-Benzyl-benzenesulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-benzamidine::CHEMBL326316

SMILES NC(=N)c1cccc(CN2CC[C@H](NS(=O)(=O)c3ccc(Cc4ccccc4)cc3)C2=O)c1

InChI Key InChIKey=BENNFWFIHBQCIH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50080474   

TargetCoagulation factor X(Human)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50080474(3-[(S)-3-(4-Benzyl-benzenesulfonylamino)-2-oxo-pyr...)
Affinity DataKi:  1.10E+3nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50080474(3-[(S)-3-(4-Benzyl-benzenesulfonylamino)-2-oxo-pyr...)
Affinity DataKi: >2.90E+3nMAssay Description:Inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50080474(3-[(S)-3-(4-Benzyl-benzenesulfonylamino)-2-oxo-pyr...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed