BDBM50080492 5-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-thiophene-3-carboxamidine::CHEMBL331939

SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2cc(cs2)C(N)=N)C1=O

InChI Key InChIKey=AVFUAEDDAJCFDH-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50080492   

TargetCoagulation factor X(Human)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50080492(5-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)
Affinity DataKi:  83nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50080492(5-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)
Affinity DataKi:  940nMAssay Description:Inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50080492(5-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetKallikrein-6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50080492(5-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed