BDBM500807 7-[[6- (3,3a,4,5,6,6a- hexahydro-2H- pyrrolo[2,3- c]pyrrol-1-yl)- 2-pyridyl]amino]- 4-(1-methylpyrrolo [2,3-b]pyridin- 4-yl)-2,3- dihydropyrrolo [3,4-c]pyridin- l-one::US11021481, Compound I-472::US11078201, Compound I-472::US11548890, Compound I-472

SMILES Cn1ccc2c(ccnc12)-c1ncc(Nc2cccc(n2)N2CCC3CNCC23)c2C(=O)NCc12

InChI Key InChIKey=BZLCROYHRWMBBX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500807   

LigandPNGBDBM500807(7-[[6- (3,3a,4,5,6,6a- hexahydro-2H- pyrrolo[2,3- ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

LigandPNGBDBM500807(7-[[6- (3,3a,4,5,6,6a- hexahydro-2H- pyrrolo[2,3- ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500807(7-[[6- (3,3a,4,5,6,6a- hexahydro-2H- pyrrolo[2,3- ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM500807(7-[[6- (3,3a,4,5,6,6a- hexahydro-2H- pyrrolo[2,3- ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500807(7-[[6- (3,3a,4,5,6,6a- hexahydro-2H- pyrrolo[2,3- ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent