BDBM50080760 (S)-2-{[4-Ethyl-2'-methyl-5-(pyridin-3-yloxymethyl)-biphenyl-2-carbonyl]-amino}-4-methylsulfanyl-butyric acid::CHEMBL122362

SMILES CCc1cc(C(=O)N[C@@H](CCSC)C(O)=O)c(cc1COc1cccnc1)-c1ccccc1C

InChI Key InChIKey=QISPGIOISYGLLE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080760   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bovine)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50080760((S)-2-{[4-Ethyl-2'-methyl-5-(pyridin-3-yloxymethyl...)Copy SMILESCopy InChI

Affinity DataIC50: 3nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL