BDBM50080794 7-[(2-p-Tolylamino-ethylamino)-methyl]-chromen-2-one::CHEMBL122754

SMILES Cc1ccc(NCCNCc2ccc3ccc(=O)oc3c2)cc1

InChI Key InChIKey=NIOLUOYPMLYKGG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50080794   

TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080794(7-[(2-p-Tolylamino-ethylamino)-methyl]-chromen-2-o...)
Affinity DataKi:  10nMAssay Description:Binding affinity using [3H]spiperone displacement from cloned human Dopamine receptor D4.2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080794(7-[(2-p-Tolylamino-ethylamino)-methyl]-chromen-2-o...)
Affinity DataIC50: 98nMAssay Description:Compound was tested for the inhibition of [3H]-thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed