BDBM50081105 Benzyl-[2-(6-chloro-2-trifluoromethyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine::CHEMBL86504

SMILES FC(F)(F)c1nc2c(OCCNCc3ccccc3)cc(Cl)cc2[nH]1

InChI Key InChIKey=MMZIPJNBJQJCBM-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50081105   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081105(Benzyl-[2-(6-chloro-2-trifluoromethyl-1H-benzoimid...)
Affinity DataKi:  0.710nMAssay Description:Inhibition of [3H]quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081105(Benzyl-[2-(6-chloro-2-trifluoromethyl-1H-benzoimid...)
Affinity DataKi:  7nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D4.4 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081105(Benzyl-[2-(6-chloro-2-trifluoromethyl-1H-benzoimid...)
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2 low affinity without GTP and sodiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081105(Benzyl-[2-(6-chloro-2-trifluoromethyl-1H-benzoimid...)
Affinity DataKi:  32nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D2 in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081105(Benzyl-[2-(6-chloro-2-trifluoromethyl-1H-benzoimid...)
Affinity DataKi:  42nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D3 in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed