BDBM50081137 7-Chloro-3-(3,5-dimethyl-phenyl)-4-[2-(1-methyl-piperidin-2-yl)-ethoxy]-6-nitro-1H-quinolin-2-one::CHEMBL314963::CHEMBL329834::CHEMBL87020

SMILES CN1CCCCC1CCOc1c(-c2cc(C)cc(C)c2)c(=[OH+])[n-]c2cc(Cl)c(cc12)[N+]([O-])=O

InChI Key InChIKey=WCHAXXSYDDEDIK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081137   

TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081137(CHEMBL314963 | CHEMBL87020 | CHEMBL329834 | 7-Chlo...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [125I]buserelin to GnRH receptor in rat pituitary membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081137(CHEMBL314963 | CHEMBL87020 | CHEMBL329834 | 7-Chlo...)
Affinity DataIC50: 32nMAssay Description:Binding affinity for Gonadotropin-releasing hormone receptor in rat pituitary membrane at 10 buserelin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081137(CHEMBL314963 | CHEMBL87020 | CHEMBL329834 | 7-Chlo...)
Affinity DataIC50: 85nMAssay Description:Binding affinity for Gonadotropin-releasing hormone receptor in rat pituitary membrane at 10 buserelin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed