BDBM50081439 CHEMBL92539::sulfonylurea analogue

SMILES CN(CCc1ccccc1)C(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2c3ccccc3CCc3ccccc3C2=O)cc1

InChI Key InChIKey=LBGFGHRPRLDYOY-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50081439   

TargetProstaglandin E2 receptor EP1 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50081439(sulfonylurea analogue | CHEMBL92539)
Affinity DataKi:  17nMAssay Description:Affinity at human EP1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50081439(sulfonylurea analogue | CHEMBL92539)
Affinity DataKi:  1.10E+3nMAssay Description:Affinity at human EP4 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50081439(sulfonylurea analogue | CHEMBL92539)
Affinity DataKi:  2.10E+3nMAssay Description:Compound was evaluated for its secondary binding affinity to human TP receptors by using Aequorin luminescence-based functional calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50081439(sulfonylurea analogue | CHEMBL92539)
Affinity DataKi:  2.87E+3nMAssay Description:Compound was evaluated for its secondary binding affinity to human DP receptors by using Aequorin luminescence-based functional calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50081439(sulfonylurea analogue | CHEMBL92539)
Affinity DataKi:  5.00E+3nMAssay Description:Affinity at human EP3 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50081439(sulfonylurea analogue | CHEMBL92539)
Affinity DataKi:  6.20E+3nMAssay Description:Compound was evaluated for its secondary binding affinity to human FP receptors by using Aequorin luminescence-based functional calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50081439(sulfonylurea analogue | CHEMBL92539)
Affinity DataKi:  2.30E+4nMAssay Description:Affinity at human EP2 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50081439(sulfonylurea analogue | CHEMBL92539)
Affinity DataKi:  5.20E+4nMAssay Description:Compound was evaluated for its secondary binding affinity to human IP receptors by using Aequorin luminescence-based functional calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed