BDBM50081804 (Difluoro-{(1R,2S)-2-[2-(6-oxo-1,6-dihydro-purin-9-yl)-ethyl]-cyclopropyl}-methyl)-phosphonic acid::CHEMBL317966

SMILES OP(O)(=O)C(F)(F)[C@@H]1C[C@H]1CCn1cnc2c1nc[nH]c2=O

InChI Key InChIKey=QVQSDTSXZCLYNT-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081804   

TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50081804((Difluoro-{(1R,2S)-2-[2-(6-oxo-1,6-dihydro-purin-9...)
Affinity DataKi:  8.80nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50081804((Difluoro-{(1R,2S)-2-[2-(6-oxo-1,6-dihydro-purin-9...)
Affinity DataIC50: 70nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in Cellulomonas spMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50081804((Difluoro-{(1R,2S)-2-[2-(6-oxo-1,6-dihydro-purin-9...)
Affinity DataIC50: 340nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in human erythrocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed