BDBM50081855 (2R,3R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-5-methyl-3-(morpholine-4-carbonyl)-hexanoic acid hydroxyamide::CHEMBL328381

SMILES CC(C)C[C@H]([C@H](CN1C(=O)c2ccccc2C1=O)C(=O)NO)C(=O)N1CCOCC1

InChI Key InChIKey=NFRICHJLQIOONF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50081855   

TargetInterstitial collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081855((2R,3R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmeth...)
Affinity DataIC50: 20nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081855((2R,3R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmeth...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Coll-3 MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081855((2R,3R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmeth...)
Affinity DataIC50: 600nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081855((2R,3R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmeth...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Gel-A MMP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081855((2R,3R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmeth...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Strom-1 MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed