BDBM50082016 2-Chloro-N-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dihydro-quinolin-3-yl)-phenyl]-acetamide::CHEMBL138159

SMILES Oc1c(-c2cccc(NC(=O)CCl)c2)c(=O)[nH]c2cc(Cl)ccc12

InChI Key InChIKey=PFXLOHFSMOMACE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082016   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082016(2-Chloro-N-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dihydr...)
Affinity DataIC50: 155nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082016(2-Chloro-N-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dihydr...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed