BDBM50082127 3-(ammoniomethyl)-2,6-difluorobenzenolate::3-Aminomethyl-2,6-difluoro-phenol::CHEMBL321931

SMILES [NH3+]Cc1ccc(F)c([O-])c1F

InChI Key InChIKey=ARLSXSJLCYMMDM-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50082127   

TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50082127(3-Aminomethyl-2,6-difluoro-phenol | 3-(ammoniometh...)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [3H]GABA from Gamma-aminobutyric acid type B receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Pig)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50082127(3-Aminomethyl-2,6-difluoro-phenol | 3-(ammoniometh...)
Affinity DataKi:  6.30E+6nMAssay Description:The compound was tested for the inhibition of Gamma-amino-N-butyrate transaminase from pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Pig)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50082127(3-Aminomethyl-2,6-difluoro-phenol | 3-(ammoniometh...)
Affinity DataKi:  6.30E+6nMAssay Description:Competitive inhibition of pig brain GABA aminotransferase by Dixon/Cornish-Bowden plot analysis in presence of GABAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50082127(3-Aminomethyl-2,6-difluoro-phenol | 3-(ammoniometh...)
Affinity DataKi:  6.30E+6nMAssay Description:Competitive inhibition of GABA aminotransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50082127(3-Aminomethyl-2,6-difluoro-phenol | 3-(ammoniometh...)
Affinity DataKi:  6.30E+6nMAssay Description:Competitive inhibition of GABA aminotransferase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed