BDBM50082355 3-Benzyl-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one::CHEMBL108802

SMILES CC1(C)OC(=O)C(Cc2ccccc2)=C1c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=KNHHNILXEQGEIW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082355   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50082355(3-Benzyl-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory potency against human COX-2 in stably transfected chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50082355(3-Benzyl-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl...)
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibitory potency against human COX-2 (HWB COX-2) by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50082355(3-Benzyl-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl...)
Affinity DataIC50: 9.00E+4nMAssay Description:In vitro inhibitory potency against human COX-1 in stably transfected chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed