BDBM50082533 4-(4-Methoxy-benzenesulfonyl)-[1,4]thiazepane-3-carboxylic acid hydroxyamide::CHEMBL140568

SMILES COc1ccc(cc1)S(=O)(=O)N1CCCSCC1C(=O)NO

InChI Key InChIKey=MRZSOAZZNSUPLS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50082533   

TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082533(4-(4-Methoxy-benzenesulfonyl)-[1,4]thiazepane-3-ca...)
Affinity DataIC50: 64nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082533(4-(4-Methoxy-benzenesulfonyl)-[1,4]thiazepane-3-ca...)
Affinity DataIC50: 1.90nMAssay Description:In vitro inhibitory activity against collagenase-3 (matrix metalloprotease-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082533(4-(4-Methoxy-benzenesulfonyl)-[1,4]thiazepane-3-ca...)
Affinity DataIC50: 4.30nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082533(4-(4-Methoxy-benzenesulfonyl)-[1,4]thiazepane-3-ca...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibitory activity against matrilysin (matrix metalloprotease-7).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed