BDBM50082536 1-(4-Methoxy-benzenesulfonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL124680

SMILES COc1ccc(cc1)S(=O)(=O)N1CCNCC1C(=O)NO

InChI Key InChIKey=NDGWYSJFTMSGNY-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50082536   

TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082536(1-(4-Methoxy-benzenesulfonyl)-piperazine-2-carboxy...)
Affinity DataIC50: 6.90nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082536(1-(4-Methoxy-benzenesulfonyl)-piperazine-2-carboxy...)
Affinity DataIC50: 2.39E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082536(1-(4-Methoxy-benzenesulfonyl)-piperazine-2-carboxy...)
Affinity DataIC50: 48nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082536(1-(4-Methoxy-benzenesulfonyl)-piperazine-2-carboxy...)
Affinity DataIC50: 175nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082536(1-(4-Methoxy-benzenesulfonyl)-piperazine-2-carboxy...)
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082536(1-(4-Methoxy-benzenesulfonyl)-piperazine-2-carboxy...)
Affinity DataIC50: 48nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082536(1-(4-Methoxy-benzenesulfonyl)-piperazine-2-carboxy...)
Affinity DataIC50: 2.39E+3nMAssay Description:In vitro inhibitory activity against matrilysin (matrix metalloprotease-7).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082536(1-(4-Methoxy-benzenesulfonyl)-piperazine-2-carboxy...)
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory activity against collagenase-3 (matrix metalloprotease-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082536(1-(4-Methoxy-benzenesulfonyl)-piperazine-2-carboxy...)
Affinity DataIC50: 175nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082536(1-(4-Methoxy-benzenesulfonyl)-piperazine-2-carboxy...)
Affinity DataIC50: 48nMAssay Description:Binding affinity towards matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed