BDBM50082558 (S)-2,2-Dimethyl-4-(4-pentyl-benzenesulfonyl)-[1,4]thiazepane-3-carboxylic acid hydroxyamide::(S)-N-hydroxy-2,2-dimethyl-4-(4-pentylphenylsulfonyl)-1,4-thiazepane-3-carboxamide::CHEMBL343082

SMILES CCCCCc1ccc(cc1)S(=O)(=O)N1CCCSC(C)(C)[C@@H]1C(=O)NO

InChI Key InChIKey=SEQZHNNPDSVBRC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50082558   

TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082558((S)-N-hydroxy-2,2-dimethyl-4-(4-pentylphenylsulfon...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082558((S)-N-hydroxy-2,2-dimethyl-4-(4-pentylphenylsulfon...)
Affinity DataIC50: 2.10nMAssay Description:In vitro inhibitory activity against collagenase-3 (matrix metalloprotease-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082558((S)-N-hydroxy-2,2-dimethyl-4-(4-pentylphenylsulfon...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibitory activity against matrilysin (matrix metalloprotease-7).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082558((S)-N-hydroxy-2,2-dimethyl-4-(4-pentylphenylsulfon...)
Affinity DataIC50: 61nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082558((S)-N-hydroxy-2,2-dimethyl-4-(4-pentylphenylsulfon...)
Affinity DataIC50: 25nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed