BDBM50082800 1-(3-{[4-Methyl-5-methylcarbamoyl-6-(4-nitro-phenyl)-2-oxo-3,6-dihydro-2H-pyrimidine-1-carbonyl]-amino}-propyl)-4-phenyl-piperidine-4-carboxylic acid methyl ester::CHEMBL145334

SMILES CNC(=O)C1=C(C)NC(=O)N(C1c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(C(=O)OC)c1ccccc1

InChI Key InChIKey=USAJHRPHUPIVLS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082800   

TargetAlpha-1A adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082800(1-(3-{[4-Methyl-5-methylcarbamoyl-6-(4-nitro-pheny...)
Affinity DataKi:  2.10nMAssay Description:In vitro binding affinity against Alpha-1A adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082800(1-(3-{[4-Methyl-5-methylcarbamoyl-6-(4-nitro-pheny...)
Affinity DataKi:  100nMAssay Description:In vitro binding affinity against Alpha-1B adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082800(1-(3-{[4-Methyl-5-methylcarbamoyl-6-(4-nitro-pheny...)
Affinity DataKi:  270nMAssay Description:In vitro binding affinity against Alpha-1D adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed