BDBM50083115 CHEMBL147907::{1-[3-(5-Imidazol-1-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-((R)-1-phenyl-ethyl)-amine

SMILES C[C@@H](NC1CCN(CCCc2c[nH]c3ccc(cc23)-n2ccnc2)CC1)c1ccccc1

InChI Key InChIKey=MIEAXBUEPZRDHB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083115   

Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083115({1-[3-(5-Imidazol-1-yl-1H-indol-3-yl)-propyl]-pipe...)
Affinity DataIC50: 4.20nMAssay Description:Displacement of [3H]5-HT binding to cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083115({1-[3-(5-Imidazol-1-yl-1H-indol-3-yl)-propyl]-pipe...)
Affinity DataIC50: 110nMAssay Description:Displacement of [3H]5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083115({1-[3-(5-Imidazol-1-yl-1H-indol-3-yl)-propyl]-pipe...)
Affinity DataEC50:  6.20nMAssay Description:Agonist-induced [35S]- GTPgammaS binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed