BDBM50083153 2-Phenyl-1'-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-[1,4']bipiperidinyl::CHEMBL147838

SMILES C(CN1CCC(CC1)N1CCCCC1c1ccccc1)Cc1c[nH]c2ccc(cc12)-n1cnnc1

InChI Key InChIKey=WGWBIIDCWJHIOA-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083153   

Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083153(2-Phenyl-1'-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-y...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [3H]5-HT binding to cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083153(2-Phenyl-1'-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-y...)
Affinity DataEC50:  4.70nMAssay Description:Agonist-induced [35S]- GTPgammaS binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083153(2-Phenyl-1'-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-y...)
Affinity DataIC50: 410nMAssay Description:Displacement of [3H]5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed