BDBM500832 4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((6- ((3aS,6aS)- hexahydropy- rrolo[3,4-b]pyrrol- 1(2H)-yl)pyridin-2- yl)amino)isoin- dolin-1-one::US11021481, Compound I-497::US11078201, Compound I-497::US11548890, Compound I-497

SMILES Fc1ccn2c(cnc2c1)-c1ccc(Nc2cccc(n2)N2CC[C@H]3CNC[C@@H]23)c2C(=O)NCc12

InChI Key InChIKey=PAKVDYFGTCCCFC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500832   

LigandPNGBDBM500832(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((6- (...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500832(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((6- (...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM500832(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((6- (...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500832(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((6- (...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500832(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((6- (...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent