BDBM50083254 CHEMBL3423058

SMILES Cc1cc2nc([nH]c2cc1C)[C@@H](CNC(=O)c1ccc(cc1Cl)-n1cnnc1)c1ccccc1

InChI Key InChIKey=DWWCPHPUDHFFPN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50083254   

TargetCoagulation factor IX(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083254(CHEMBL3423058)
Affinity DataKi:  16nMAssay Description:Inhibition of human factor 9a using CH3SO2-D-CHG-Gly-Arg-AFC.AcOH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2016
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083254(CHEMBL3423058)
Affinity DataKi:  16nMAssay Description:Inhibition of human coagulation factor 9a using fluorescent peptide CH3SO2-D-CHG-Gly-Arg-AFC-AcoH as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083254(CHEMBL3423058)
Affinity DataKi:  390nMAssay Description:Inhibition of human factor 10a using n-Acetyl-KPR-AFC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083254(CHEMBL3423058)
Affinity DataKi:  394nMAssay Description:Inhibition of human coagulation factor 10a using fluorescent peptide nAcetyl-KPR-AFC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed