BDBM50083739 CHEMBL115707::{(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-carbamoyl}-3-[(5-methyl-pyrazine-2-carbonyl)-amino]-propyl}-carbamic acid benzyl ester

SMILES Cc1cnc(cn1)C(=O)NCC[C@@H](NC(=O)OCc1ccccc1)C(=O)NCC(=O)N[C@H]1CCCN(C1O)C(N)=N

InChI Key InChIKey=JXPPFBLPIXIHCM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50083739   

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083739({(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...)
Affinity DataIC50: 106nMAssay Description:In vitro inhibition of human Factor Xa.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083739({(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of human thrombolytic protease Plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083739({(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083739({(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of human Thrombin (FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed