BDBM50083741 CHEMBL419222::{(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-carbamoyl}-3-[(1H-pyrazole-4-carbonyl)-amino]-propyl}-carbamic acid benzyl ester

SMILES NC(=N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCNC(=O)c2cn[nH]c2)NC(=O)OCc2ccccc2)C1O

InChI Key InChIKey=ZDTHZVKHOUXASU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50083741   

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083741({(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...)
Affinity DataIC50: 75nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083741({(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...)
Affinity DataIC50: 346nMAssay Description:In vitro inhibition of human Factor Xa.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083741({(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of human Thrombin (FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083741({(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...)
Affinity DataIC50: 3.27E+3nMAssay Description:In vitro inhibition of human thrombolytic protease Plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed