BDBM50083746 CHEMBL117716::Quinoline-2-carboxylic acid ((R)-3-{[((S)-1-carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-carbamoyl}-3-phenylmethanesulfonylamino-propyl)-amide

SMILES NC(=N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCNC(=O)c2ccc3ccccc3n2)NS(=O)(=O)Cc2ccccc2)C1O

InChI Key InChIKey=RMSOJTRFERBDMB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50083746   

TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083746(Quinoline-2-carboxylic acid ((R)-3-{[((S)-1-carbam...)
Affinity DataIC50: 59nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083746(Quinoline-2-carboxylic acid ((R)-3-{[((S)-1-carbam...)
Affinity DataIC50: 1.44E+3nMAssay Description:In vitro inhibition of human thrombolytic protease Plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083746(Quinoline-2-carboxylic acid ((R)-3-{[((S)-1-carbam...)
Affinity DataIC50: 44nMAssay Description:In vitro inhibition of human Factor Xa.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083746(Quinoline-2-carboxylic acid ((R)-3-{[((S)-1-carbam...)
Affinity DataIC50: 1.27E+3nMAssay Description:In vitro inhibition of human Thrombin (FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed