BDBM50083757 CHEMBL302366::Isomer of 4b,12-Difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-6b-[2-(2-oxo-tetrahydro-furan-3-ylsulfanyl)-acetyl]-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one::Isomer of4b,12-Difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-6b-[2-(2-oxo-tetrahydro-furan-3-ylsulfanyl)-acetyl]-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one

SMILES CC1(C)O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CSC1CCOC1=O

InChI Key InChIKey=XAXUUHRSYQHGOZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083757   

TargetGlucocorticoid receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50083757(Isomer of 4b,12-Difluoro-5-hydroxy-4a,6a,8,8-tetra...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of [3H]dexamethasone binding to human Glucocorticoid ReceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50083757(Isomer of 4b,12-Difluoro-5-hydroxy-4a,6a,8,8-tetra...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of [3H]dexamethasone binding to human Glucocorticoid ReceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed