BDBM50084201 (R)-4-[(Z)-tert-Butoxyimino]-1-(4-methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL151718

SMILES COc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OC(C)(C)C

InChI Key InChIKey=WXUQPWYPRTYWIR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084201   

Target72 kDa type IV collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084201((R)-4-[(Z)-tert-Butoxyimino]-1-(4-methoxy-benzenes...)
Affinity DataIC50: 0.700nMAssay Description:In vitro inhibitory activity against gelatinase-A (matrix metalloprotease-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084201((R)-4-[(Z)-tert-Butoxyimino]-1-(4-methoxy-benzenes...)
Affinity DataIC50: 9nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084201((R)-4-[(Z)-tert-Butoxyimino]-1-(4-methoxy-benzenes...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloprotease-1, MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084201((R)-4-[(Z)-tert-Butoxyimino]-1-(4-methoxy-benzenes...)
Affinity DataIC50: 263nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloprotease-7, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed