BDBM50084210 (R)-1-[4-(2-Methoxy-ethoxy)-benzenesulfonyl]-4-methylene-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL358405

SMILES COCCOc1ccc(cc1)S(=O)(=O)N1CC(=C)C[C@@H]1C(=O)NO

InChI Key InChIKey=RQEBSVZFRXVOLZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50084210   

Target72 kDa type IV collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084210((R)-1-[4-(2-Methoxy-ethoxy)-benzenesulfonyl]-4-met...)
Affinity DataIC50: 9nMAssay Description:In vitro inhibitory activity against gelatinase-A (matrix metalloprotease-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084210((R)-1-[4-(2-Methoxy-ethoxy)-benzenesulfonyl]-4-met...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of human recombinant collagenase-3 (Matrix metalloprotease-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084210((R)-1-[4-(2-Methoxy-ethoxy)-benzenesulfonyl]-4-met...)
Affinity DataIC50: 69nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084210((R)-1-[4-(2-Methoxy-ethoxy)-benzenesulfonyl]-4-met...)
Affinity DataIC50: 1.55E+3nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloprotease-1, MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084210((R)-1-[4-(2-Methoxy-ethoxy)-benzenesulfonyl]-4-met...)
Affinity DataIC50: 9.99E+3nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloprotease-7, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed