BDBM50084221 (R)-4-[(Z)-Methoxyimino]-1-(4-propoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL151539

SMILES CCCOc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OC

InChI Key InChIKey=NVNGYUBMJMOHQL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084221   

TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084221((R)-4-[(Z)-Methoxyimino]-1-(4-propoxy-benzenesulfo...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084221((R)-4-[(Z)-Methoxyimino]-1-(4-propoxy-benzenesulfo...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloprotease-1, MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084221((R)-4-[(Z)-Methoxyimino]-1-(4-propoxy-benzenesulfo...)
Affinity DataIC50: 381nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloprotease-7, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed