BDBM50084285 2-(4'-Bromo-biphenyl-4-sulfonylamino)-propionic acid::CHEMBL432307

SMILES C[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O

InChI Key InChIKey=UJVIDDIDLMDARE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084285   

TargetCollagenase 3(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084285(2-(4'-Bromo-biphenyl-4-sulfonylamino)-propionic ac...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084285(2-(4'-Bromo-biphenyl-4-sulfonylamino)-propionic ac...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084285(2-(4'-Bromo-biphenyl-4-sulfonylamino)-propionic ac...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084285(2-(4'-Bromo-biphenyl-4-sulfonylamino)-propionic ac...)
Affinity DataIC50: 9.50E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084285(2-(4'-Bromo-biphenyl-4-sulfonylamino)-propionic ac...)
Affinity DataIC50: 1.10E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084285(2-(4'-Bromo-biphenyl-4-sulfonylamino)-propionic ac...)
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed